Muriel, a former bestselling romantic novelist, and Ruth, a journalist, are best friends. Inseparable since they were little, theyve shared everything; unable to be without each other, even after the most vicious of fights. Now fate has left them living together in a North London home, with Ruth caring for Muriel in her deteriorating health, playing Scrabble, arguing and making up, passing the days in monotony, ignoring the scars of their relationship. Then one afternoon, Muriel makes a shocking and sinister announcement, sending Ruths world into chaos. Only one thing is certain. Life, as she knows it, will never be the same again.
